Title:
UCF1 DERIVATIVE
Document Type and Number:
Japanese Patent JPH04221377
Kind Code:
A
Abstract:
PURPOSE: To obtain a UCF1 derivative useful as an antimicrobial agent and an antitumor agent, having antimicrobial action and antitumor action.
CONSTITUTION: A compound shown by formula I (R is group shown by formula II or formula III). The compound shown by formula I wherein R is group shown by formula II is referred to as UCF1-AX and the compound shown by formula II wherein R is group shown by formula III as UCF1-BX. For example, UCF1- AX is obtained by reacting UCF1-A with chromium oxide as an oxidizing agent (1-10 equivalents based on UCF1-A) in a mixed solvent of acetic acid and dimethyl sulfoxide at 0-50°C for 1-24 hours, isolating and purifying by column chromatography, etc.
Inventors:
NAKANO HIROFUMI
HARA MITSUNOBU
SAITO YUTAKA
INATA YOJI
TAKIGUCHI TOSHIMITSU
OKABE MASAMI
HARA MITSUNOBU
SAITO YUTAKA
INATA YOJI
TAKIGUCHI TOSHIMITSU
OKABE MASAMI
Application Number:
JP8503591A
Publication Date:
August 11, 1992
Filing Date:
April 17, 1991
Export Citation:
Assignee:
KYOWA HAKKO KOGYO KK
International Classes:
A61K31/335; A61K31/336; A61P31/04; A61P35/00; C07D303/36; C12P17/02; C12R1/465; (IPC1-7): A61K31/335; C07D303/36; C12P17/02
Previous Patent: 内燃機関のガス交換弁を操作するための弁調節装置
Next Patent: 5-FLUORO-1,3-DIOXIN-4-ONE DERIVATIVE AND INTERMEDIATE THEREOF
Next Patent: 5-FLUORO-1,3-DIOXIN-4-ONE DERIVATIVE AND INTERMEDIATE THEREOF