Title:
尿素誘導体及びその用途
Document Type and Number:
Japanese Patent JPWO2017038873
Kind Code:
A1
Abstract:
本発明は、ディスコイジンドメイン受容体１に対して阻害活性を有する化合物を提供することを目的としている。本発明は、下式に代表される尿素誘導体又はその薬理学的に許容される塩を提供する。
Inventors:
Nishio Yukihiro
Kubota Yuko
Masashi Yamamoto
Hiroshi Nishimura
Tomohide Masuda
Hideyuki Tsutsui
Keiichi Okimura
Shuji Udagawa
Mie Kaino
Hiroyuki Meguro
Yumiko Kamiya
Kubota Yuko
Masashi Yamamoto
Hiroshi Nishimura
Tomohide Masuda
Hideyuki Tsutsui
Keiichi Okimura
Shuji Udagawa
Mie Kaino
Hiroyuki Meguro
Yumiko Kamiya
Application Number:
JP2016556023A
Publication Date:
June 14, 2018
Filing Date:
August 31, 2016
Export Citation:
Assignee:
TORAY INDUSTRIES,INC.
International Classes:
C07C275/34; A61K31/17; A61K31/44; A61K31/4406; A61K31/4409; A61K31/4412; A61K31/4427; A61K31/4439; A61K31/4545; A61K31/50; A61K31/505; A61K31/506; A61K31/5377; A61P35/00; A61P35/04; A61P43/00; C07D213/30; C07D213/65; C07D213/74; C07D213/82; C07D237/14; C07D239/34; C07D239/47; C07D401/04; C07D401/12; C07D403/12; C07D405/12; C07D405/14
Foreign References:
| WO2015038778A1 | 2015-03-19 | |||
| CN102319242A | 2012-01-18 | |||
| WO2014032755A2 | 2014-03-06 |
Other References:
TING CHEN, ET AL.: "Explorations of Substituted Urea Functionality for the Discovery of New Activators of the Heme-Regul", JOURNAL OF MEDICINAL CHEMISTRY, vol. 56, no. 23, JPN6016044404, 21 November 2013 (2013-11-21), pages 9457 - 9470, XP055366582, ISSN: 0004208169, DOI: 10.1021/jm400793v
Attorney, Agent or Firm:
Patent Service Corporation Tanigawa International Patent Office