Title:
虚血再灌流障害を予防するためのC1インヒビターの使用
Document Type and Number:
Japanese Patent JP5394748
Kind Code:
B2
Abstract:
The present invention relates to the therapeutic and prophylactic use of Cl inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The Cl inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
Inventors:
Mannesse Morris
Niens Johannes Henrix
Peeper Frank
Desimoni Maria Grazia
Siele Heiss Berthas Johannes
Niens Johannes Henrix
Peeper Frank
Desimoni Maria Grazia
Siele Heiss Berthas Johannes
Application Number:
JP2008547134A
Publication Date:
January 22, 2014
Filing Date:
December 19, 2006
Export Citation:
Assignee:
PHARMING INTELLECTUAL PROPERTY B.V.
International Classes:
A61K38/55; A61K45/00; A61P1/00; A61P9/00; A61P9/10; A61P13/12; A61P25/00
Domestic Patent References:
| JP2003521914A |
Foreign References:
| WO2004100982A1 |
Other References:
SCHERER M.,ANN.THORAC.SURG.,2002年,V73,P233-238
ZWAAN DE C,EUROPEAN HEART JOURNAL,THE EUROPEAN SOCIETY OF CARDIOLOGY,2002年,V23,P1670-1677
FRIESECKE S,INTENSIVMEDIZIN,2002年,V39 N7,P610-616
CICARDI M,SPRINGER SEMINAR IN IMMUNOPATHOLOGY,ドイツ,SPRINGER VERLAG,2005年11月 3日,V27,P286-298
STORINI C.,NEUROBIOLOGY OF DISEASE,2005年,V19,P10-17
AKITA N.,NEUROSURGERY,2003年 2月,V52 N2,P395-401
ZWAAN DE C,EUROPEAN HEART JOURNAL,THE EUROPEAN SOCIETY OF CARDIOLOGY,2002年,V23,P1670-1677
FRIESECKE S,INTENSIVMEDIZIN,2002年,V39 N7,P610-616
CICARDI M,SPRINGER SEMINAR IN IMMUNOPATHOLOGY,ドイツ,SPRINGER VERLAG,2005年11月 3日,V27,P286-298
STORINI C.,NEUROBIOLOGY OF DISEASE,2005年,V19,P10-17
AKITA N.,NEUROSURGERY,2003年 2月,V52 N2,P395-401
Attorney, Agent or Firm:
Masaki Hirota
Seiji Ozawa
Yusaku Tokai
High Kazuya Tsu
Makoto Horiuchi
Seiji Ozawa
Yusaku Tokai
High Kazuya Tsu
Makoto Horiuchi