Title:
プリオンベースの疾患を治療するための塩素グアナベンズ誘導体の使用
Document Type and Number:
Japanese Patent JP5186503
Kind Code:
B2
Abstract:
The invention relates to chlorine Guanabenz derivatives for treating prion-based diseases. More specifically, it relates to the use of the molecule of formula (I) wherein R = H or Cl and the phenyl group is at least substituted twice, or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for treating prion-based diseases.
Inventors:
Blondel marc
Back stephan
Villette Didier
Verang Vincent
Tribeir Deborah
Back stephan
Villette Didier
Verang Vincent
Tribeir Deborah
Application Number:
JP2009530967A
Publication Date:
April 17, 2013
Filing Date:
October 03, 2007
Export Citation:
Assignee:
Saintur Nacional De La Rousche Châtantique Séenneres
Institut Nacional de la Rushche Agronomic
Institut Nacional de la Rushche Agronomic
International Classes:
A61K31/155; A61P25/28; C07C281/18
Domestic Patent References:
| JP2006502745A | ||||
| JP2004528324A | ||||
| JP2010505814A | ||||
| JP2009529488A |
Foreign References:
| WO2003006426A1 | ||||
| WO2001000212A1 | ||||
| US6413962 |
Other References:
BACH,S.,ET AL.,"Isolation of drugs active against mammalian prions using a yeast-based screening assay",NATURE BIOTECHNOLOGY,2003年 9月 1日,VOL.21,NO.9,PP.1075-1081
Attorney, Agent or Firm:
Einosuke Kishimoto
Akira Watanabe
Matsumura Naoto
Akira Watanabe
Matsumura Naoto