Title:
幹細胞を単離または生成するためのマーカーとしてのIslet1の使用
Document Type and Number:
Japanese Patent JP2006519015
Kind Code:
A
Abstract:
The present invention provides in vitro methods of expansion and propagation of undifferentiated progenitor cells and more specifically undifferentiated progenitor cells containing Islet1, a marker apparently unique to proliferating cardiac stem cells. Methods are described for isolation of stem cell populations as well as for provoking expansion and propagation of undifferentiated progenitor cells without differentiation, to provide cardiac repair or improve cardiac function, for example.
Inventors:
Evans Silvia M.
Change
Kai Shen Ren
Moretti Alessandra
Chien Kenneth Earl.
Rogue Witz Curl-Ludwig
Change
Kai Shen Ren
Moretti Alessandra
Chien Kenneth Earl.
Rogue Witz Curl-Ludwig
Application Number:
JP2006503268A
Publication Date:
August 24, 2006
Filing Date:
February 02, 2004
Export Citation:
Assignee:
The Regents of The University of California
International Classes:
C12Q1/68; C12N5/00; C12N5/02; C12N5/077; C12N5/10; C12Q1/02; G01N33/53; G01N33/543; G01N33/569; C12N15/09; C12N
Domestic Patent References:
| JP2004526449A | 2004-09-02 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi