Title:
免疫療法に使用する医薬の製造におけるSerrateまたはDeltaの使用
Document Type and Number:
Japanese Patent JP4339406
Kind Code:
B2
Abstract:
The present invention relates to the use of therapeutic compounds in the modification of T-cell, T-cell-antigen presenting cell (APC) interactions and the interactions between pathogenic organisms and immunocompetent cells of a host. In particular it relates to the use of these compounds in the modulation of the interaction between Notch proteins and their ligands and to the use of such compounds in the therapy of conditions such as graft rejection, autoimmunity, allergy, and asthma and infectious diseases.
Inventors:
Lamb, Jonathan, Robert
Dalman, Margaret, Jane
Hoyne, Gerald, Francis
Dalman, Margaret, Jane
Hoyne, Gerald, Francis
Application Number:
JP52115098A
Publication Date:
October 07, 2009
Filing Date:
November 06, 1997
Export Citation:
Assignee:
CELLDEX THERAPEUTICS LTD.
International Classes:
C07K14/705; C12N15/02; A61K38/00; A61K39/00; A61K45/00; A61P1/16; A61P31/04; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P33/00; A61P33/06; A61P37/02; A61P37/04; A61P37/06; A61P37/08; C07K14/725; C07K16/28; C07K19/00; C12N5/18; C12N15/09; C12N15/63; G01N33/50; G01N33/68
Other References:
Nature, vol. 375, pp.761-766 (1995)
Nature, vol. 375, pp.787-790 (1995)
Development, vol. 121, pp. 2407-2418 (1995)
Cell, vol. 80, pp. 909-917 (1995)
Nature, vol. 375, pp. 787-790 (1995)
Nature, vol. 375, pp.787-790 (1995)
Development, vol. 121, pp. 2407-2418 (1995)
Cell, vol. 80, pp. 909-917 (1995)
Nature, vol. 375, pp. 787-790 (1995)
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Ishii Teiji