Title:
Use of the activity of PI3K, or inhibitor of a function
Document Type and Number:
Japanese Patent JP6117235
Kind Code:
B2
Abstract:
The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.
Inventors:
Cook, Nigel Graham
Fernandez Gomez dos Santos, Paul Antonio
Furette, Pascal
Christina Hebach
Haguenauer, Clemens
Holling Worth, Gregory
Charis, christophe
Louis, Ian
Smith, alexander buckster
Soldierman, Nicholas
Frederick, Stuffer
Strang, ross
Stowasser, frank
Nachola Tafiri
Phonemat, Annette
Roman, wolf
Zedri, Frederick
Fernandez Gomez dos Santos, Paul Antonio
Furette, Pascal
Christina Hebach
Haguenauer, Clemens
Holling Worth, Gregory
Charis, christophe
Louis, Ian
Smith, alexander buckster
Soldierman, Nicholas
Frederick, Stuffer
Strang, ross
Stowasser, frank
Nachola Tafiri
Phonemat, Annette
Roman, wolf
Zedri, Frederick
Application Number:
JP2014546719A
Publication Date:
April 19, 2017
Filing Date:
December 14, 2012
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K31/519; A61P33/06; A61P43/00
Domestic Patent References:
| JP2009544664A | ||||
| JP2010532320A | ||||
| JP5770842B2 |
Foreign References:
| WO2009058361A1 | ||||
| WO2010036908A1 |
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Yasuhito Suzuki
Norio Omori
Yasuhito Suzuki