Title:
Use of the antioxidants in the method and means for detecting the target molecule in a blood sample
Document Type and Number:
Japanese Patent JP6272327
Kind Code:
B2
Abstract:
The present invention relates to a method for detection of at least one target molecule in a blood sample comprising at least the following steps: (a) providing a blood sample; (b1) contacting said sample with an antioxidant and applying said sample to a filter to separate the blood cells from said sample; and/or (b2) applying said sample to a filter to separate the blood cells from said sample, wherein said filter comprises an antioxidant; (c) contacting said sample with a first binding molecule in the cartridge, wherein said first binding molecule is attached to a magnetic particle, and wherein said first binding molecule is capable of specifically binding to said at least one target molecule; (d) contacting said sample with a second binding molecule, wherein said second binding molecule is attached to a sensor surface, and wherein said second binding molecule is capable of specifically binding to said at least one target molecule; and (e) detecting the magnetic particles on the sensor surface. The present invention also relates to the use of an antioxidant in the process of detection of at least one target molecule in a blood sample as well as to cartridges for insertion into an assay device for detection of at least one target molecule in a blood sample.
Inventors:
Detjee, Femke Carina
Fissels, Jost Lambert Max
Fissels, Jost Lambert Max
Application Number:
JP2015527043A
Publication Date:
January 31, 2018
Filing Date:
August 08, 2013
Export Citation:
Assignee:
KONINKLIJKE PHILIPS N.V.
International Classes:
G01N33/543; G01N33/53; G01N33/553
Domestic Patent References:
| JP4293506A |
Foreign References:
| WO2011077333A1 | ||||
| US20070077548 | ||||
| EP2052736A1 |
Other References:
VERONIQUE JARRIGE ET AL.,A fast intraoperative PTH point-of-care assay on the Philips handheld magnotech system,LANGENBECK'S ARCHIVES OF SURGERY,2010年12月21日,vol.396,no.3,PP.337-343
Attorney, Agent or Firm:
Tadashige Ito
Tadahiko Ito
Shinsuke Onuki
Tadahiko Ito
Shinsuke Onuki