Use as complex aromatic compounds and its dopamine D1 ligand

Title:

Use as complex aromatic compounds and its dopamine D1 ligand

Document Type and Number:

Japanese Patent JP6190076

Kind Code:

B2

Abstract:

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression.

Inventors:

David Lawrence Furman Gray
Ray Jean
Jennifer elizabeth davolen
Amy Beth Downey
Ivan Victorovich Efremov
Scott Richard Maintain
Chakra Pannie Sabraman Yum

Application Number:

JP2016564057A

Publication Date:

August 30, 2017

Filing Date:

April 09, 2015

Export Citation:

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Assignee:

Pfizer Inc.

International Classes:

C07D471/04; A61K31/437; A61K31/444; A61K31/497; A61K31/4985; A61K31/501; A61K31/506; A61K31/519; A61P25/00; A61P25/04; A61P25/06; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P43/00; C07D491/048; C07D495/04; C07D513/04; C07D519/00

Domestic Patent References:

JP2007537296A
JP5857168B2
JP5823657B2
JP2017513881A

Foreign References:

CN102558147A
WO2009079412A2

Other References:

Egypt. J. Pharm. Sci.,1997年,Vol.38, No.4-6,p.319-331
Medicinal Research Reviews,2009年,Vol.29, No.2,p.272-294

Attorney, Agent or Firm:

Noh four
Junko Miyazawa
Maki Sato
Tatsuta Miyuki

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