Title:
式Iで示される少なくとも1種のイソキノリン化合物の使用、神経変性疾患を治療または予防するための医薬組成物、および、神経変性疾患を治療または予防する方法
Document Type and Number:
Japanese Patent JP2013517301
Kind Code:
A
Abstract:
The present invention concern the use of isoquinoline alkaloid compounds of formula I in the preparation of pharmaceutical compositions useful in the treatment of neurodegenerative diseases, particularly Alzheimer's disease, as well as pharmaceutical composition comprising said compounds and method of treatment of neurodegenerative diseases.
wherein R 1 is -OH or -OCH 3 , and X is non-existent, HCl or HBr, including their isomers,
Inventors:
Luis Francisco Pianowski
Joanne Batista Calixto
Jean A. Grinski
Joanne Batista Calixto
Jean A. Grinski
Application Number:
JP2012549211A
Publication Date:
May 16, 2013
Filing Date:
January 19, 2011
Export Citation:
Assignee:
Luis Francisco Pianowski
Joanne Batista Calixto
Jean A. Grinski
Joanne Batista Calixto
Jean A. Grinski
International Classes:
A61K31/473; A61P25/28
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Akiko Nakahama
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Akiko Nakahama