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Title:
ヒトおよび動物におけるIGF-1血清レベルの低下と関連した種々の疾患状態の治療用の治療用組成物の製造のための血清中IGF-1レベルを増加できる化合物の使用
Document Type and Number:
Japanese Patent JP4641942
Kind Code:
B2
Abstract:
The present disclosure relates to the use of one or more compounds that are capable of increasing the serum level of insulin-like growth factor 1 (IGF-1) for the preparation of a therapeutical composition, in particular, in the form of a food supplement, for the treatment of subjects suffering from serious fatigue and exhausting symptoms, burn-out and chronic fatigue syndrome. The same composition can also be used by patients suffering from depression, Alzheimer disease, irritated bowel syndrome, osteoporosis, type 2 diabetes, or for anti-aging, immune therapy and recovery after exercise. The composition also has a use in veterinary applications for increasing the growth and immunity in animals.

Inventors:
Hubert Jean-Marie Francois Zilsen
Application Number:
JP2005509805A
Publication Date:
March 02, 2011
Filing Date:
October 03, 2003
Export Citation:
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Assignee:
Veijlen N.V.
International Classes:
A61K31/405; A23K1/16; A23K1/18; A61K9/48; A61K31/404; A61K31/4045; A61K31/7056; A61P1/00; A61P3/02; A61P3/10; A61P5/00; A61P19/10; A61P25/24; A61P25/28; A61P37/00; A61P37/02; A61P39/00; A61P43/00; C07D209/18
Domestic Patent References:
JP2001026539A
JP7503232A
JP2001518481A
JP7025838A
JP2002281914A
JP7506559A
JP2002524402A
JP2003137808A
JP8308580A
JP2002525265A
JP11512395A
Foreign References:
FR2741799A1
Other References:
SELTZER, HOLBROOKE S. and SMITH, WALTER L.,"Plasma insulin activity" in human diabetes during hypoglycemic response to tolbutamide and indole-3-acetic acid,PROC SOC EXPTL AND MED,1959年,vol.100, no.1,p.171-174 (abstract),BIOSIS [online]; [retrieved on 28 June 2010] BIOSIS Accession no. 1959:29265
Cancer Research,2003年,Vol.63,p.776-779
Bioorganic and Medicinal Chemistry Letters,2002年,Vol.12,p.2523-2526
Attorney, Agent or Firm:
Mitsuo Tanaka
Masaki Yano