Title:
細胞の異常消失に関わる障害の治療のための、および/または、肥満の治療のためのGIP活性を有する化合物の使用
Document Type and Number:
Japanese Patent JP2006502100
Kind Code:
A
Abstract:
Abstract of the Disclosure Use of a compound having 50% activity or more of the activity of gastric inhibitory polypeptide, GIP, when tested in the same assay under the same conditions, and/or the use of GIP, analogues and fragments thereof, for the manufacture of a pharmaceutical composition for prophylaxis and/or treatment of conditions caused or characterized by abnormal loss of cells and/or for prophylaxis and/or treatment of over weight and obesity. A compound as described above for the prophylaxis and/or treatment of over weight and obesity. Use of antagonists to GIP or the GIP receptor for the prophylaxis and/or treatment of disorders caused or characterized by hyperproliferation of cells and/or abnormally low body weight. A compound for the manufacture of a composition for prophylaxis and/or treatment of depression and/or mood disorders, and a method for determining the level of GIP in the brain of a mammal, is also included.
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Inventors:
Nyberg, Jenny
Ericsson, Peter
Ericsson, Peter
Application Number:
JP2004510816A
Publication Date:
January 19, 2006
Filing Date:
June 11, 2003
Export Citation:
Assignee:
EISAI CO.,LTD.
International Classes:
A61K45/00; A61K38/00; A61K38/17; A61K38/22; A61K39/395; A61P1/00; A61P1/02; A61P1/16; A61P1/18; A61P3/04; A61P3/10; A61P5/00; A61P7/00; A61P9/00; A61P9/08; A61P9/10; A61P11/00; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P17/00; A61P17/02; A61P17/06; A61P19/00; A61P19/02; A61P21/00; A61P25/00; A61P25/02; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P27/02; A61P29/00; A61P31/18; A61P35/00; A61P35/02; A61P43/00; C07K14/47; C07K14/575; C12N15/09
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Junko Kobayashi
Norio Omori
Eiji Katayama
Junko Kobayashi
Norio Omori