Title:
統合失調症治療のためのシクロオキシゲナーゼ-2選択的阻害剤の使用
Document Type and Number:
Japanese Patent JP2007511572
Kind Code:
A
Abstract:
The invention concerns the use of compounds of formula (I), (II) and (III) which are COX-2 (cyclooxygenase-2) inhibitors, and pharmaceutically acceptable salts and solates thereof, for the treatment of schizophrenic disorders. Schizophrenic disorders of the invention are to be intended schizophrenia, delusional disorders, affective disorders, autism or tic disorders, schizophreniform disorders, in particular chronic schizophrenic psychoses and schizoaffective psychoses, temporary acute psychotic disorders. Moreover, the invention is concerned with the use of a pyrimidine derivative known as COX-2 inhibitor in combination with a neuroleptic drug for the treatment of schizophrenic disorders such as those defined above.
Inventors:
James Hargan
Carol rootledge
Carol rootledge
Application Number:
JP2006540321A
Publication Date:
May 10, 2007
Filing Date:
November 17, 2004
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
A61K31/4418; A61K31/44; A61K31/4439; A61K31/444; A61K31/5025; A61K31/505; A61K31/513; A61K45/00; A61P21/02; A61P25/18; A61P43/00; C07D213/64; C07D213/74; C07D239/34; C07D401/12; C07D487/04
Foreign References:
| WO2002096885A1 | 2002-12-05 | |||
| WO2002102297A2 | 2002-12-27 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Tadayuki Motoyama
Kenji Tomita
Tadayuki Motoyama
Kenji Tomita