Title:
β-グルカンの使用
Document Type and Number:
Japanese Patent JP4578393
Kind Code:
B2
Abstract:
The invention provides methods of using beta glucans to treat conditions associated with bone loss or low bone density as well as methods for promoting bone growth in situations where enhanced bone growth is desirable. In the invention methods beta glucans are administered so as to enhance the development of osteoblasts and the inhibition of the development and recruitment of osteoclasts. The inhibition of the recruitment and development of osteoclasts, coupled with the enhancement of osteoblast maturation by beta glucans leads to decreased bone resorption and increased bone formation, making beta glucans ideal agents for the treatment of osteoporosis and other bone resorption diseases.
Inventors:
Gunter Harald El.
Gunter Honey Roll E.
Solgent Nino
Gunter Honey Roll E.
Solgent Nino
Application Number:
JP2005347307A
Publication Date:
November 10, 2010
Filing Date:
November 30, 2005
Export Citation:
Assignee:
Momentum Pharmaceuticals
Imdyne incorporated
Imdyne incorporated
International Classes:
C12P19/04; A61K31/592; A61K31/715; A61K33/06; A61K33/16; A61K33/22; A61K31/716; A61P19/10
Domestic Patent References:
| JP2002209598A | ||||
| JP2001354570A | ||||
| JP9512708A | ||||
| JP8500623A |
Foreign References:
| EP0875580A1 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi