Title:
創傷癒合を促進させる薬物の製造のための高張液組成物の使用
Document Type and Number:
Japanese Patent JP2010514707
Kind Code:
A
Abstract:
A use of a hypertonic solution composition in manufacturing medicaments used during the perioperative period for promoting wound healing, said composition consists of 1.5%-6.9% (w/v) of one or more substances selected from sodium chloride, sodium bicarbonate, potassium chloride, magnesium sulfate, calcium chloride and calcium gluconate, 3%-18%(w/v) of one or more of the substances selected from hydroxyethyl starch, dextran, carboxymethyl starch, polyvinyl pyrrolidone and gelatin derivatives, and the remainder of conventional injection, provided that the amount of sodium chloride in the composition is not less than 1,5%(w/v), and the concentration of sodium ion is not more than the one equivalent to the concentration of sodium ion in 6.9% (w/v) sodium chloride solution. The hypertonic solution composition can be administered as transfusion before operation, during operation, after operation with the dose of 100-1500ml/person/day, which can promoter wound healing. The hypertonic solution composition is advantageous in terms of the safety and convenience of application. Said composition can applied to various operative wounds or trauma wound (surface) as well as anastomotic stoma.
Inventors:
Jiao, Chaoin
Application Number:
JP2009543334A
Publication Date:
May 06, 2010
Filing Date:
December 19, 2007
Export Citation:
Assignee:
Jiao, Chaoin
International Classes:
A61K47/02; A61K9/08; A61K47/10; A61K47/12; A61K47/18; A61K47/26; A61K47/32; A61K47/34; A61K47/36; A61K47/42; A61L31/00; A61P41/00
Attorney, Agent or Firm:
Takehiko Suzue
Kurata Masatoshi
Satoshi Kono
Makoto Nakamura
Yoshihiro Fukuhara
Takashi Mine
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Katsu Sunagawa
Tetsuya Kazama
Kurata Masatoshi
Satoshi Kono
Makoto Nakamura
Yoshihiro Fukuhara
Takashi Mine
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Katsu Sunagawa
Tetsuya Kazama