Title:
Use in a scripter Idoa iso star (SCRIPTAIDISOSTERES) and its medical treatment
Document Type and Number:
Japanese Patent JP5981956
Kind Code:
B2
Abstract:
Compounds of the invention are of the formula wherein: is a double bond and X is C; or is a single bond and X is N, CH or CQR1; and wherein: n is 1 to 10; R is H or QR1; each R′ is independently selected from H and QR1; each Q is independently selected from a bond, CO, NH, S, SO, SO2 or O; each R1 is independently selected from C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, substituted or unsubstituted aryl or heteroaryl, acyl, C1-C10 cycloalkyl, halogen, C1-C10 alkylaryl or C1-C10 heterocycloalkyl; L is a nitrogen-containing heteroaryl; and W is a zinc-chelating residue; or a pharmaceutically acceptable salt thereof. The compounds are useful in therapy.
Inventors:
Shuttle Worth, Stephen Joseph
Tomassi, Cyril Davi
Tomassi, Cyril Davi
Application Number:
JP2014100193A
Publication Date:
August 31, 2016
Filing Date:
May 14, 2014
Export Citation:
Assignee:
Callus Therapeutics Limited
International Classes:
C07D213/54; A61K31/444; A61K31/4709; A61K45/00; A61P1/00; A61P1/02; A61P1/04; A61P3/10; A61P7/00; A61P7/02; A61P7/06; A61P9/00; A61P9/04; A61P9/12; A61P13/10; A61P15/00; A61P17/02; A61P17/10; A61P19/02; A61P25/00; A61P29/00; A61P31/00; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P43/00; C07D213/74; C07D401/12
Domestic Patent References:
| JP5597649B2 | ||||
| JP2008542428A |
Foreign References:
| WO2008055068A1 |
Other References:
Biosensors & Bioelectronics (1996), 11(3), 305-315
Bioorganic & Medicinal Chemistry Letters (2009), 19(10), 2840-2843
Bioorganic & Medicinal Chemistry Letters (2009), 19(10), 2840-2843
Attorney, Agent or Firm:
Atsushi Nakajima
Kato Kazunori
Katsuichi Nishimoto
Kato Kazunori
Katsuichi Nishimoto
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