Title:
喘息、COPD、および他の疾患の処置におけるインドール-3-酢酸の使用
Document Type and Number:
Japanese Patent JP2005525327
Kind Code:
A
Abstract:
The invention relates to N-substituted indole-3-acetic acid derivatives of the general formula in which R1 is optionally substituted benzothiazolyl, pyrimidin-4-yl, imidazol-2-yl, oxazol-2-yl or thiazol-2-yl, R2 is hydrogen, halogen, C1-6alkyl or C1-6alkoxy and R3 is hydrogen or C1-6alkyl (see further details in the description), and their use in the treatment of respiratory diseases such as asthma, rhinitis and chronic obstructive pulmanory disease (COPD), and other diseases mediated by prostaglandin D2(PGD2).
Inventors:
Andrew Baxter
John Steel
Simon Teague
John Steel
Simon Teague
Application Number:
JP2003565471A
Publication Date:
August 25, 2005
Filing Date:
February 04, 2003
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
C07D403/04; A61K31/405; A61K31/426; A61K31/428; A61K31/506; A61P1/04; A61P1/16; A61P3/04; A61P3/10; A61P7/04; A61P9/10; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P11/10; A61P13/12; A61P17/00; A61P17/04; A61P17/06; A61P17/08; A61P19/00; A61P19/02; A61P19/08; A61P21/00; A61P21/02; A61P21/04; A61P25/00; A61P25/06; A61P25/14; A61P25/28; A61P27/02; A61P29/00; A61P31/00; A61P31/02; A61P31/04; A61P31/08; A61P31/14; A61P31/18; A61P31/20; A61P37/00; A61P37/06; A61P37/08; A61P41/00; A61P43/00; C07D417/04; (IPC1-7): C07D403/04; A61K31/428; A61K31/506; A61P1/04; A61P1/16; A61P3/04; A61P3/10; A61P7/04; A61P9/10; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P11/10; A61P13/12; A61P17/00; A61P17/04; A61P17/06; A61P17/08; A61P19/00; A61P19/02; A61P19/08; A61P21/00; A61P21/02; A61P21/04; A61P25/00; A61P25/06; A61P25/14; A61P25/28; A61P27/02; A61P29/00; A61P31/00; A61P31/02; A61P31/04; A61P31/08; A61P31/14; A61P31/18; A61P31/20; A61P37/00; A61P37/06; A61P37/08; A61P41/00; A61P43/00; C07D417/04
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima