Title:
痴呆関連疾患、アルツハイマー病およびグリコーゲンシンターゼキナーゼ-3関連症状の治療におけるオキシインドール誘導体の使用
Document Type and Number:
Japanese Patent JP4393196
Kind Code:
B2
Abstract:
The present invention relates to a new use of oxindole derivatives of formula I, as a free base or a pharmaceutically acceptable salt thereof, [Chemical formula should be inserted here. Please see paper copy.] wherein R1, R2, R3, m and n are as defined as in claim 1, as well as to new compounds, a process for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said therapeutically active compounds and to the use of said active compounds in therapy, especially in the prevention and/or treatment of dementia related diseases, Alzheimer's Disease and conditions associated with glycogen synthase kinase-3.
Inventors:
Stefan Bellui
Rattan Burt
Philip Edwards
Sven Helberg
Rattan Burt
Philip Edwards
Sven Helberg
Application Number:
JP2003556069A
Publication Date:
January 06, 2010
Filing Date:
December 18, 2002
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
C07D239/86; A61K31/496; A61K31/517; A61K31/5377; A61P9/10; A61P15/16; A61P15/18; A61P17/14; A61P21/04; A61P25/14; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P43/00; C07D209/34; C07D239/88; C07D239/90; C07D239/93; C07D295/185; C07D403/04; C07D403/14; C07D405/14
Domestic Patent References:
| JP2000510115A | ||||
| JP10505600A | ||||
| JP2000515114A | ||||
| JP2000517291A |
Foreign References:
| WO2001064681A1 |
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Junji Yuda
Shoji Miwa
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