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Title:
USE OF PREGNANE AND ANDROSTANE STEROIDS FOR PRODUCTION OF PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CNS DISORDERS
Document Type and Number:
Japanese Patent JP2013173781
Kind Code:
A
Abstract:

To provide a steroid compound suitable for treatment of CNS disorders, and a method for production thereof.

There is provided a compound of formula I having unsaturation between C4 and C5 or C5 and C6, its pharmaceutically acceptable salt or its solvate [wherein R1 is ethynyl or hydroxyl; R2 is also ethynyl or hydroxyl; R3 does not exist; R4 is hydroxyl; R5 is proton, or R4 and R5 together form keto (=O) or N as oxime (=NOH); R6 is methyl; R7 is H; R8 is methyl or H; and R9 is methyl or H, or does not exist when the unsaturation is present between C4 and C5].


Inventors:
TORBJOERN BAECKSTROEM
RAGAGNIN GIANNA
Application Number:
JP2013097485A
Publication Date:
September 05, 2013
Filing Date:
May 07, 2013
Export Citation:
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Assignee:
UMECRINE AB
International Classes:
C07J7/00; A61K31/57; A61P3/02; A61P3/04; A61P5/24; A61P15/00; A61P19/08; A61P21/00; A61P25/00; A61P25/08; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/00
Foreign References:
WO1998005337A11998-02-12
Attorney, Agent or Firm:
Seiji Ohno
Reiko Tanaka
Yuko Matsuniya
Ken Kitano
Natsuki Ito