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Title:
化学療法への反応を予測するための2つの抗SPARC抗体の使用
Document Type and Number:
Japanese Patent JP5886191
Kind Code:
B2
Abstract:
The invention provides anti-SPARC antibody-based techniques for predicting a response to chemotherapy.

Inventors:
Chew, Vong
Desai, Neil
Nower, Daniel
Application Number:
JP2012513301A
Publication Date:
March 16, 2016
Filing Date:
May 28, 2010
Export Citation:
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Assignee:
Abraxis Bioscience, LLC
International Classes:
A61K31/282; G01N33/574; A61K31/337; A61K31/7068; A61K45/00; A61P1/18; A61P17/00; A61P35/00; A61P35/02; C12Q1/02; G01N33/53
Domestic Patent References:
JP2006517926A
JP2007531500A
JP2013505268A
Foreign References:
WO2008060651A2
Other References:
Gronborg M, Kristiansen TZ, Iwahori A, Chang R, Reddy R, Sato N, Molina H, Jensen ON, Hruban RH, Goggins MG, Maitra A, Pandey A.,Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach.,Mol Cell Proteomics.,2006年,Vol.5,No.1,Page.157-171
Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R.,SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration.,J Leukoc Biol. ,2007年,Vol.81,No.3,Page.748-756
Infante JR, Matsubayashi H, Sato N, Tonascia J, Klein AP, Riall TA, Yeo C, Iacobuzio-Donahue C, Goggins M.,Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma.,J Clin Oncol. ,2007年 1月20日,Vol.25,No.3,Page.319-325
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki
Junzo Koike
Hirofumi Toma