Title:
サイクリン依存性キナーゼ阻害剤としての、5-チオ-、スルフィニル-およびスルホニルピラゾロ[3,4-b]-ピリジンの用途
Document Type and Number:
Japanese Patent JP2004507455
Kind Code:
A
Abstract:
The present invention describes compounds of formula (I):and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and n are as defined above. Compounds of formula (I) are protein kinase inhibitors and are useful in the treatment of proliferative diseases, for example, cancer, inflammation and arthritis. They may also be useful in the treatment of Alzheimer's disease and cardiovascular disease.
Inventors:
Raj N Mithra
Application Number:
JP2001578438A
Publication Date:
March 11, 2004
Filing Date:
April 13, 2001
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
A61K31/437; A61K45/00; A61P1/04; A61P1/16; A61P3/10; A61P7/00; A61P9/00; A61P9/06; A61P9/10; A61P13/12; A61P17/06; A61P17/14; A61P19/02; A61P19/10; A61P21/00; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P31/10; A61P31/12; A61P35/00; A61P37/02; A61P43/00; C07D487/04; C07D471/04; (IPC1-7): C07D471/04; A61K31/437; A61K45/00; A61P1/04; A61P1/16; A61P3/10; A61P7/00; A61P9/00; A61P9/06; A61P9/10; A61P13/12; A61P17/06; A61P17/14; A61P19/02; A61P19/10; A61P21/00; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P31/10; A61P31/12; A61P35/00; A61P37/02; A61P43/00
Attorney, Agent or Firm:
Aoyama Aoi
Osamu Kawamiya
Kyousei Tamura
Osamu Kawamiya
Kyousei Tamura