Title:
ワクチン送達方法
Document Type and Number:
Japanese Patent JP6290992
Kind Code:
B2
Abstract:
The present invention relates to a vaccine composition comprising:(i) a peptide hydrogel that is a liquid at room temperature and a gel at physiological pH, physiological salt concentrations and/or physiological temperatures; and (ii) one or more antigens; wherein the peptide hydrogel comprises a self-assembling peptide selected from the group consisting of RAD16-I ((RADA)(4); (SEQ ID NO:2)), RAD16-II ((RARADADA)(2); (SEQ ID NO:3)), KFE-8 ((FKFE)(2); (SEQ ID NO:4)), and KLD-12 ((KLDL)(3)); (SEQ ID NO:5)).
Inventors:
Donald A. Hahn
Rafaela Keiros
Lisa McWen
Rafaela Keiros
Lisa McWen
Application Number:
JP2016152910A
Publication Date:
March 07, 2018
Filing Date:
August 03, 2016
Export Citation:
Assignee:
University of Georgia Research Foundation Incorporated
International Classes:
A61K39/39; A61K39/015; A61K39/02; A61K39/145; A61K39/29; A61P31/00; A61P31/04; A61P31/12; A61P33/00; A61P37/04
Foreign References:
| US5670483 |
Other References:
PNAS,2010年,vol.107, no.2,p.622-627
Vaccine,2004年,vol.22,pp.2396-2405,DOI 10.1016/j.vaccine.2003.11.064
Journal of Immunology,2011年 4月 1日,vol.186, no.1, SUpp. Meeting Abstracts,Abstract Number:155.13.
Drug Discovery Today,2007年,vol.12,p.561-568
PNAS,2005年,vol.102, no.24,p.8414-8419
Vaccine,2004年,vol.22,pp.2396-2405,DOI 10.1016/j.vaccine.2003.11.064
Journal of Immunology,2011年 4月 1日,vol.186, no.1, SUpp. Meeting Abstracts,Abstract Number:155.13.
Drug Discovery Today,2007年,vol.12,p.561-568
PNAS,2005年,vol.102, no.24,p.8414-8419
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Tatsunori Ikeda
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Tatsunori Ikeda