Title:
VACCINE FOR ZOSTER VIRUS
Document Type and Number:
Japanese Patent JPS62285792
Kind Code:
A
Abstract:
A gene of varicella-zoster virus (VZV) which encodes immunogenic outer surface viral proteins has been identified by DNA sequence analysis. Antibodies directed against peptides imputed from the DNA sequence can react with the glycoprotein, which itself is reactive with neutralizing antibodies. The amino-terminal sequence of the purified glycoprotein is identical to a portion of the amino acid sequence imputed from the DNA sequence. This glycoprotein is useful for the preparation of a vaccine against VZV.
Inventors:
POORU EMU KERAA
RONARUDO DABURIYU ERISU
ROBAATO ESU ROU
MAAKU DABURIYU RIIMEN
ANDORIYUU JIEE DEEIBUISON
RONARUDO DABURIYU ERISU
ROBAATO ESU ROU
MAAKU DABURIYU RIIMEN
ANDORIYUU JIEE DEEIBUISON
Application Number:
JP10877787A
Publication Date:
December 11, 1987
Filing Date:
May 01, 1987
Export Citation:
Assignee:
MERCK & CO INC
International Classes:
C07K14/03; A61K39/25; A61P31/12; C07H21/04; C07K14/00; C07K14/04; C12N1/15; C12N1/18; C12N1/20; C12N1/21; C12N5/00; C12N5/10; C12N15/00; C12N15/09; C12N15/38; C12P21/02; A61K39/00; C12R1/91; C12R1/92; (IPC1-7): A61K39/25; C07H21/04; C07K13/00; C12N5/00; C12N15/00; C12P21/02; C12R1/91
Attorney, Agent or Firm:
Masao Okabe