Title:
FVIIおよびFVIIaの変種
Document Type and Number:
Japanese Patent JP4847856
Kind Code:
B2
Abstract:
The invention relates to variants of FVII or FVlla comprising at least one amino acid modification in position 341 relative to HFVII or hFVIIa. The variants exhibit an increased clotting activity, i.e. reduced clotting time, compared to rhFVIIa.
Inventors:
Andersen Kim Bilbo
Repke Mass
Harning Jesper Mortensen
Glazer Steven
Repke Mass
Harning Jesper Mortensen
Glazer Steven
Application Number:
JP2006504332A
Publication Date:
December 28, 2011
Filing Date:
March 22, 2004
Export Citation:
Assignee:
BAYER HEALTHCARE
International Classes:
C12N15/09; A61K38/43; A61K38/48; A61P7/04; A61P41/00; C07K14/435; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/64; C12N15/57
Foreign References:
| WO2001058935A2 | 2001-08-16 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki