Title:
バリセラ・ゾースターウィルス抗原
Document Type and Number:
Japanese Patent JP3990445
Kind Code:
B2
Abstract:
The present invention relates to the construction of a recombinant plasmid which is capable of expressing a secretory truncated glycoprotein (Tgp) of Varicella-zoster virus (VZV) in mammalian cells. The secretory Tgp of the present invention contains at least one epitope capable of inducing antibody response. The present invention contemplates the production and utilization of this secretory Tgp in a vaccine against chickenpox and/or shingles. The present invention is also directed towards the use of the secretory Tgp in diagnostic assays for detection of VZV. The present invention is also directed to first antibodies specific to secretory Tgp and to second antibodies specific to the first antibodies. These second antibodies are also useful in diagnostic assays for VZV.
Inventors:
Baffei, Abbas
Application Number:
JP51806591A
Publication Date:
October 10, 2007
Filing Date:
October 04, 1991
Export Citation:
Assignee:
Research Corporation Technologies Incorporated
International Classes:
A61K38/00; C12N15/09; A61K39/245; A61K39/25; A61K39/395; A61K49/00; A61P31/22; A61P37/04; C07K14/00; C07K14/03; C07K14/04; C07K16/00; C07K16/08; C12N5/10; C12N15/38; C12P21/02; C12P21/04; C12P21/08; C12Q1/70; G01N33/53; G01N33/569; A61K39/00; C12R1/91
Domestic Patent References:
| JP349694A | ||||
| JP3232897A | ||||
| JP6181792A | ||||
| JP1252279A |
Other References:
Virus Res.,Vol.13,No.4(1989)p.319-336
J.Virol.,Vol.62,No.8(1988)p.2544-2551
Virology,Vol.178,No.1(1990)p.263-272
Virus Res.,Vol.10,No.2-3(1988)p.205-213
J.Virol.,Vol.62,No.8(1988)p.2544-2551
Virology,Vol.178,No.1(1990)p.263-272
Virus Res.,Vol.10,No.2-3(1988)p.205-213
Attorney, Agent or Firm:
Takehiko Saito