To obtain a new vinyltin compound capable of producing rostaglandins useful as e.g. a swine-oxytocic with a few processes and an inexpensive reaction reagent, by reaction of a protecting group-bearing specific epoxysilicon compound with an organotin metal salt.
This new compound is the optically active or racemic form of a new vinyltin compound of formula I [R1 to R3 are each a 1-12C (substituted) alkyl or (substituted) phenyl; R4 is a protecting group for hydroxyl group] [e.g. (3R)-1-(tri-n-butylstannyl)-3-(triphenylsilyloxy)-4-(m-chlorophenoxy)-1-trans- butene]. This compound is useful as e.g. a reaction reagent capable of producing prostaglandins useful as e.g. a swine-oxytocic with a few processes at low cost. This compound is obtained by reaction the optically active or racemic form of a protecting group-bearing epoxysilicon compound of formula II (R6 to R8 are each the same kind as R1) with an organotin compound of formula III (M1 is an alkali metal).
FUJITA KUNIHIKO
MINAMII MASAYOSHI
