Title:
ボルチオキセチンのパモ酸塩及びその結晶形
Document Type and Number:
Japanese Patent JP6669932
Kind Code:
B2
Abstract:
The present application provides a vortioxetine pamoic acid salt, which includes a crystal form, a solvate or an amorphous substance of the vortioxetine pamoic acid salt. The present application provides a preparation method and use of the vortioxetine pamoic acid salt and the crystal form thereof. The vortioxetine pamoic acid salt prepared in the present application prolongs the residence time of the vortioxetine in vivo, achieving a slow release of the vortioxetine in vivo, and is suitable for preparing a long-acting dosage form.
Inventors:
Yunfei Li
Shaoea Shea
Shin Shu
Zen Jean
Ray Liu
Xiao Juan Jean
Limin Jean
Dongsheng Li
Ijin Wan
Jien Ge
Shaoea Shea
Shin Shu
Zen Jean
Ray Liu
Xiao Juan Jean
Limin Jean
Dongsheng Li
Ijin Wan
Jien Ge
Application Number:
JP2019502131A
Publication Date:
March 18, 2020
Filing Date:
March 28, 2017
Export Citation:
Assignee:
Shanghai Synergy Pharmaceutical Sciences Company Limited
International Classes:
C07D295/096; A61K31/495; A61P25/00; A61P25/04; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/34; A61P29/00
Domestic Patent References:
| JP2009541216A | ||||
| JP9509145A |
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe