Title:
高いバイオアベイラビリティを有する水溶性クルクミン混合物およびその調製方法と応用
Document Type and Number:
Japanese Patent JP7286191
Kind Code:
B2
Abstract:
A method for preparing a water-soluble curcumin mixture with high bioavailability includes the following steps: A) dissolving curcumin, vitamin C and ascorbyl palmitate in an ethanol aqueous solution, evaporating ethanol under reduced pressure, and vacuum drying to obtain a curcumin-vitamin C-ascorbyl palmitate co-crystal; B) high-speed emulsifying the curcumin-vitamin C-ascorbyl palmitate co-crystal and a wall material colloidal solution under vacuum, sequentially conducting a two-stage wet grinding, a homogenization and a potential adjustment to obtain an emulsified body; and C) subjecting the emulsified body to microencapsulation with a wall material twice and drying to obtain the water-soluble curcumin.
Inventors:
Li Hong Ron
Jin, Jen
Re, Linzhen
Shu, Shao Sung
One, Di
Yi Chun Feng
Jean, Wenjin
Sha, Fuichin
Jin, Jen
Re, Linzhen
Shu, Shao Sung
One, Di
Yi Chun Feng
Jean, Wenjin
Sha, Fuichin
Application Number:
JP2021158141A
Publication Date:
June 05, 2023
Filing Date:
September 28, 2021
Export Citation:
Assignee:
HENAN ZHONGDA HENGYUAN BIOTECHNOLOGY STOCK CO., LTD.
International Classes:
A61K9/50; A23L33/105; A61K31/12; A61K47/22; A61K47/26; A61K47/36; A61K47/38; A61K47/40; A61P9/00; A61P29/00; A61P35/00; A61P39/06
Domestic Patent References:
| JP2017516764A | ||||
| JP2009195198A | ||||
| JP2009263638A |
Foreign References:
| WO2020030612A1 | ||||
| CN105768071A | ||||
| CN105054076A | ||||
| CN107303005A |
Attorney, Agent or Firm:
Patent Attorney Corporation R&C