Title:
１１−β−ヒドロキシステロイドデヒドロゲナーゼ１型酵素の阻害薬としてのアダマンチル誘導体
Document Type and Number:
Japanese Patent JP5607021
Kind Code:
B2
Abstract:
The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
Inventors:
ジヨテイ Earl Patel
Chee シヨアイ
James テイー link
Jeffrey Jaye load
Jurgen デインゲス
Brian Kay Sorensen
Martin Win
Hong Yong
The Vince S イエー
Chee シヨアイ
James テイー link
Jeffrey Jaye load
Jurgen デインゲス
Brian Kay Sorensen
Martin Win
Hong Yong
The Vince S イエー
Application Number:
JP2011288226A
Publication Date:
October 15, 2014
Filing Date:
December 28, 2011
Export Citation:
Assignee:
アッヴィ, Incorporated
International Classes:
A61K31/16; C07C237/24; A61K31/165; A61K31/18; A61K31/196; A61K31/277; A61K31/40; A61K31/41; A61K31/42; A61K31/44; A61K31/5375; A61P3/04; A61P3/06; A61P3/10; A61P43/00; C07C235/18; C07C259/16; C07C311/02; C07C311/29; C07C311/33; C07C311/51; C07C317/22; C07C317/30; C07C317/44; C07C323/30; C07C323/62; C07D213/75; C07D233/64; C07D239/47; C07D257/04; C07D277/28; C07D295/08; C07D295/22
Attorney, Agent or Firm:
In the patent business corporation Kawaguchi 國 case, it is a patent firm.