Title:
アデノウイルスベクター
Document Type and Number:
Japanese Patent JP7187451
Kind Code:
B2
Abstract:
The present invention provides recombinant adenoviral vectors, immunogenic compositions thereof and their uses in medicine. In particular, the present invention provides an adenoviral vector comprising the genome of an adenovirus other than AdHu5 and AdY25, wherein the genome of the adenovirus has been modified such that the vector lacks the native E4 locus of the adenovirus and comprises heterologous E4Orf1, E4Orf2 and E4Orf3 coding regions from AdY25.
Inventors:
Gilbert, Sarah, Sea
Hill, adrian, boueys
Cottingham, Matthew, Gee
Dicks, matthew
Morris, susan, jay
Douglas, Alexander
Hill, adrian, boueys
Cottingham, Matthew, Gee
Dicks, matthew
Morris, susan, jay
Douglas, Alexander
Application Number:
JP2019520507A
Publication Date:
December 12, 2022
Filing Date:
June 23, 2017
Export Citation:
Assignee:
OXFORD UNIVERSITY INNOVATION LIMITED
International Classes:
C12N15/861; A61K35/761; A61K39/002; A61K39/008; A61K39/04; A61K39/205; A61K39/21; A61P31/12; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P33/02; A61P33/06; C07K4/02; C07K4/04; C07K4/12; C07K14/01; C07K14/045; C07K14/075; C07K14/08; C07K14/11; C07K14/195; C07K14/44; C07K14/445; C12N5/10; C12N7/01; C12N9/10; C12N15/113; C12N15/34; C12N15/64
Other References:
PLOS ONE,2012年,Vol.7, No.7, e40385,p.1-12
EUROPEAN JOURNAL OF IMMUNOLOGY,2012年,Vol.42, No.12,p.3243 - 3255
VACCINE,2015年,Vol.33, No.9,p.1121 - 1128
EUROPEAN JOURNAL OF IMMUNOLOGY,2012年,Vol.42, No.12,p.3243 - 3255
VACCINE,2015年,Vol.33, No.9,p.1121 - 1128
Attorney, Agent or Firm:
Patent Attorney Corporation Shuwa Patent Office