Title:
βアミロイド蛋白産生・分泌阻害剤
Document Type and Number:
Japanese Patent JP4329905
Kind Code:
B2
Abstract:
Provided are novel compounds having an inhibitory activity against production or secretion of beta -amyloid protein. They embrace compounds represented by the following formula (1): and capable of being replaced with a variety of substituents; and salts thereof, and solvates of any one of them.
Inventors:
Takanori Yasukawachi
Masayuki Ito
Hideki Kubota
Satoshi Miyauchi
Saito Regular
Masayuki Ito
Hideki Kubota
Satoshi Miyauchi
Saito Regular
Application Number:
JP2003556382A
Publication Date:
September 09, 2009
Filing Date:
December 27, 2002
Export Citation:
Assignee:
Daiichi Sankyo Co., Ltd.
International Classes:
C07D213/32; A61K31/341; A61K31/351; A61K31/352; A61K31/357; A61K31/37; A61K31/381; A61K31/382; A61K31/40; A61K31/4015; A61K31/41; A61K31/4174; A61K31/4184; A61K31/421; A61K31/426; A61K31/428; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4425; A61K31/443; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/4453; A61K31/4465; A61K31/451; A61K31/4545; A61K31/47; A61K31/495; A61K31/505; A61K31/5375; A61K31/5377; A61K31/541; A61K31/695; A61P25/28; C07C311/28; C07C317/14; C07C317/18; C07C317/20; C07C317/22; C07C317/44; C07C323/65; C07D207/325; C07D211/24; C07D211/54; C07D213/34; C07D213/53; C07D213/56; C07D213/61; C07D213/63; C07D213/65; C07D213/71; C07D213/74; C07D213/82; C07D213/89; C07D215/12; C07D215/36; C07D233/54; C07D233/64; C07D233/68; C07D233/84; C07D235/06; C07D235/28; C07D239/26; C07D239/38; C07D257/04; C07D263/22; C07D263/32; C07D277/26; C07D277/36; C07D277/76; C07D295/08; C07D295/096; C07D295/18; C07D307/10; C07D307/38; C07D309/04; C07D309/08; C07D311/56; C07D319/06; C07D333/18; C07D335/02; C07D401/04; C07D401/06; C07D401/12; C07D405/04; C07D405/06; C07D405/12; C07D409/12; C07D413/04; C07F7/18; C07D207/32
Domestic Patent References:
JP6056780A | ||||
JP6025168A | ||||
JP55033473A | ||||
JP54030174A |
Foreign References:
US4675316 | ||||
DE2855661A | ||||
EP0005754A1 | ||||
WO2000031021A1 | ||||
WO2001019797A1 | ||||
WO2001060826A1 | ||||
WO2001082967A1 |
Other References:
Journal of Heterocyclic Chemistry,1997年,34(6),p.1741-1752
Tetrahedron,1995年,51(30),p.8339-8354
Heterocycles,1995年,41(4),p.641-646
Synthesis,1991年,(12),p.1221-1227
Chemische Berichte,1989年,122(1),p.105-111
Khimiya Geterotsiklicheskikh Soedinenii ,1968年,(1),p.53-57
Tetrahedron,1995年,51(30),p.8339-8354
Heterocycles,1995年,41(4),p.641-646
Synthesis,1991年,(12),p.1221-1227
Chemische Berichte,1989年,122(1),p.105-111
Khimiya Geterotsiklicheskikh Soedinenii ,1968年,(1),p.53-57
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Asano Yasutaka
Hiromi Matoba
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Asano Yasutaka
Hiromi Matoba