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Patent Searching and Data


Title:
An antibody and its use
Document Type and Number:
Japanese Patent JP6128535
Kind Code:
B2
Abstract:
An antibody provided by the present invention has a low reactivity with amyloid precursor proteins, and has a higher reactivity with amylospheroids than with amyloid ² fibrils or monomeric amyloid ²-proteins. According to the present invention, an antibody is provided that has a higher reactivity with amylospheroids than with amyloid precursor proteins, and has any one or more of the following properties: (i) a higher activity with amylospheroids than with amyloid ² fibrils; (ii) a higher reactivity with amylospheroids than with monomeric amyloid ²-proteins; and (iii) an activity of inhibiting neuronal cell death induced by amylospheroids.

Inventors:
星 美奈子
佐藤 道夫
井手野 祥次
内藤 幸嗣
保理江 智
野田 宗宏
堀井 肇
Application Number:
JP2015106830A
Publication Date:
May 17, 2017
Filing Date:
May 26, 2015
Export Citation:
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Assignee:
TAOヘルスライフファーマ株式会社
International Classes:
C07K16/18; A61K39/395; A61P25/28; C07K16/46; C12N5/16; C12N15/02; C12N15/09; C12P21/08; G01N33/15; G01N33/50
Domestic Patent References:
JP2001247600A
JP2002105099A
Foreign References:
WO2006016644A1
Attorney, Agent or Firm:
特許業務法人池内・佐藤アンドパートナーズ