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Title:
An autoimmune disease medical treatment agent which consists of PD-1 agonist
Document Type and Number:
Japanese Patent JP6278224
Kind Code:
B2
Abstract:
Provided is a prophylactic, symptom progress suppressive, and/or therapeutic agent for an autoimmune disease. The agent lowers the risk of infections and reduces the burden of administration to patients. The prophylactic, symptom progress-suppressive, and/or therapeutic agent includes a PD-1 agonist as an active ingredient and is administered (a) 1 to 10 times within one month from the first administration, (b) in a total PD-1 agonist dose of 20 to 1250 µg/kg, and (c) without requiring administration for at least 3 months after the last administration.

Inventors:
Shiro Shibayama
Masai Imai
Application Number:
JP2017024163A
Publication Date:
February 14, 2018
Filing Date:
February 13, 2017
Export Citation:
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Assignee:
Ono Pharmaceutical Co., Ltd.
International Classes:
A61K39/395; A61P3/10; A61P5/48; A61P7/06; A61P17/00; A61P17/06; A61P19/02; A61P21/00; A61P25/00; A61P29/00; A61P37/06; C07K16/28; C07K16/46
Domestic Patent References:
JP2010229134A
Foreign References:
WO2003011911A1
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office