Title:
A cell death depressant and a manufacturing method for the same
Document Type and Number:
Japanese Patent JP6263815
Kind Code:
B2
Abstract:
Provided is a cell-death inhibitor including, as an active ingredient thereof, a compound represented by formula (1), and/or a compound represented by formula (2). The cell-death inhibitor exhibits high cell-death inhibition activity.
Inventors:
Ayano Sato
Yuta Nishina
Yuta Nishina
Application Number:
JP2015504347A
Publication Date:
January 24, 2018
Filing Date:
March 05, 2014
Export Citation:
Assignee:
Okayama University
International Classes:
A61K31/404; A61K31/423; A61P1/16; A61P9/10; A61P43/00
Foreign References:
| WO2001074807A1 |
Other References:
SIBGATULIN,D.A. et al,Reaction of enamines with trifluoromethyl containing carbonyl reagents,Journal of Fluorine Chemistry,2010年,vol.131, no.2,p.190-199
KAWASE, M. et al,Alpha-trifluoromethylated acyloins induce apoptosis in human oral tumor cell lines,Bioorg Med Chem Lett,1999年,vol.9, no.21,p.3113-8
KAWASE, M. et al,Alpha-trifluoromethylated acyloins induce apoptosis in human oral tumor cell lines,Bioorg Med Chem Lett,1999年,vol.9, no.21,p.3113-8
Attorney, Agent or Firm:
Shigeki Nakatsugu
Shunichiro Ito
Shunichiro Ito