The constituent containing indoleamine 2 for treating an autoimmune obstacle or the pain by internal-organs immunity refusal, and at least two compounds which guide 3-dioxy Genase (IDO)

Title:

The constituent containing indoleamine 2 for treating an autoimmune obstacle or the pain by internal-organs immunity refusal, and at least two compounds which guide 3-dioxy Genase (IDO)

Document Type and Number:

Japanese Patent JP6063392

Kind Code:

B2

Abstract:

The invention relates to the use of a composition comprising at least two compounds, each of which induces indolamine 2,3-dioxygenase, for the treatment of an autoimmune disorder or disease or immune rejection of transplants or gene therapeutically modified cells, wherein said inducers have different mechanism of action and wherein the composition gives rise to a synergistic effect on the IDO levels.

Inventors:

Salfold, Reif
Faegren, Hans Olof
Vedegren, Bent

Application Number:

JP2013546073A

Publication Date:

January 18, 2017

Filing Date:

December 20, 2011

Export Citation:

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Assignee:

Idogen AB

International Classes:

C12N5/07; A61K31/7072; A61K35/12; A61K35/15; A61K38/21; A61K38/24; A61P37/06; A61P43/00; C12N5/0784; C12N5/0786

Foreign References:

WO2008147283A1

Other References:

HEYES, M. P.,Annals New York Academy of Sciences,2006年,Vol.679, No.1,p.211-6
TAKIKAWA, O.,Biochemical and Biophysical Research Communications,2005年,Vol.338,p.12-9
Blood,2005年,Vol.106, No.7,p.2375-81
Journal of Reproductive Immunology,2008年,Vol.77,p.117-25
Biology of Reproduction,2007年,Vol.76,p.639-44
Journal of Interferon and Cytokine Research,2000年,Vol.20,p.369-76
Journal of Interferon and Cytokine Research,2005年,Vol.25,p.20-30
Handbook of Experimental Pharmacology,2009年,Vol.188,p.165-96

Attorney, Agent or Firm:

Patent business corporation Kita Aoyama International

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