Title:
副腎皮質ステロイドの経口送達のための組成物
Document Type and Number:
Japanese Patent JP5608641
Kind Code:
B2
Abstract:
An oral drug delivery composition includes a sustained release component which includes a corticosteroid drug and which is contained within a capsule that has been treated so that the sustained release component is predominately released from the capsule in the intestine following oral administration. A drug delivery composition for delivering a corticosteroid drug to the intestine also includes: (a) a sustained release component comprising a corticosteroid drug, an alkali-containing ethylcellulose material and an acid; and (b) a delayed release component which substantially prevents release of the sustained release component until the composition reaches the intestine following oral administration. The compositions of the invention are useful for treating inflammatory diseases of the gastrointestinal tract, such as Crohn's disease and ulcerative colitis, and for treating glomerulonephritis.
Inventors:
Peter Watts
Ann marguerite Dyer
Ann marguerite Dyer
Application Number:
JP2011508995A
Publication Date:
October 15, 2014
Filing Date:
May 07, 2009
Export Citation:
Assignee:
Archimedes development Limited
International Classes:
A61K31/58; A61K9/62; A61K47/12; A61K47/14; A61K47/26; A61K47/32; A61K47/36; A61K47/38; A61P1/04; A61P13/12; A61P29/00
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Jitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Jitsuhiro