Title:
KITS AND METHODS FOR DETECTING MICROORGANISMS RESISTANT TO THERAPEUTIC AGENTS
Document Type and Number:
Japanese Patent JP2017113018
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods for detecting microorganisms resistant to therapeutic agents in biological samples.SOLUTION: Provided is a method for detecting a microorganism resistant to a therapeutic agent comprising the steps of: a) inoculating a biological sample into a first tube containing at least one therapeutic agent and into a second tube not containing the therapeutic agent, where the tubes preferably contain at least a solvent, a buffer and/or a suitable culture medium, or tubes are serum separating tubes, and incubating the sample; b) adding a fluorescent marker to the first and second tubes; and c) carrying out fluorescence analysis to each of the first and second tubes to obtain one or more fluorescence and growth parameter(s), where the biological sample with microorganisms of resistant phenotype to the therapeutic agent can be determined by comparing the one or more fluorescence parameters between the two tubes.SELECTED DRAWING: None
Inventors:
CIDALIA IRENE AZEVEDO PINA VAZ
ACACIO AGOSTINHO GONCALVES RODRIGUES
ISABEL CRISTINA SANTOS SILVA DE FARIA RAMOS ANTUNES
RITA MAFALDA DOS SANTOS ROCHA DO ROSARIO
ANA SOFIA QUINTA E COSTA DE OLIVEIRA MORAIS
ANA TERESA PINTO E SILVA
ACACIO AGOSTINHO GONCALVES RODRIGUES
ISABEL CRISTINA SANTOS SILVA DE FARIA RAMOS ANTUNES
RITA MAFALDA DOS SANTOS ROCHA DO ROSARIO
ANA SOFIA QUINTA E COSTA DE OLIVEIRA MORAIS
ANA TERESA PINTO E SILVA
Application Number:
JP2017027372A
Publication Date:
June 29, 2017
Filing Date:
February 16, 2017
Export Citation:
Assignee:
UNIV DO PORTO
International Classes:
C12M1/34; C12Q1/04
Domestic Patent References:
| JPS60500557A | 1985-04-25 | |||
| JP2008086279A | 2008-04-17 | |||
| JP2007093614A | 2007-04-12 | |||
| JP2011523546A | 2011-08-18 |
Foreign References:
| WO2009095258A1 | 2009-08-06 | |||
| EP0118274A1 | 1984-09-12 |
Other References:
C PINA-VAZ: "SAFE SUSCEPTIBILITY TESTING OF MYCOBACTERIUM TUBERCULOSIS BY FLOW CYTOMETRY 以下備考", JOURNAL OF MEDICAL MICROBIOLOGY, vol. V54 N1, JPN5014007012, 1 January 2005 (2005-01-01), pages 77 - 81, ISSN: 0003952012
藤村享滋ら、日本化学療法学会雑誌、２００５年、５３巻Ｓ−１号、５７−７０頁, JPN6016005061, ISSN: 0003952018
C.PINA-VAZ, ET AL., J CLIN MICROBIOL, 2004, 42(2), PP906-908, JPN6016005057, ISSN: 0003952019
PINA-VAZ C: "CYTOMETRIC APPROACH FOR A RAPID EVALUATION OF SUSCEPTIBILITY OF CANDIDA STRAINS TO ANTIFUNGALS", CLINICAL MICROBIOLOGY AND INFECTION, vol. V7 N11, JPN5014007013, 1 November 2001 (2001-11-01), pages 609 - 618, ISSN: 0003952013
C.PINA-VAZ, ET AL., J MED MICROBIOL, 2001, 50, PP375-382, JPN6016005048, ISSN: 0003952014
A.FAVEL, ET AL., J ANTIMICROBIAL CHEMOTHERAPY, 1999, 43, PP227-232, JPN6016005050, ISSN: 0003952015
F.PEYRON, ET AL., ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41(7), PP1537-1540, JPN6016005052, ISSN: 0003952016
石井良和、モダンメディア、２００７年、５３巻４号、８−１４頁, JPN6016005055, ISSN: 0003952017
藤村享滋ら、日本化学療法学会雑誌、２００５年、５３巻Ｓ−１号、５７−７０頁, JPN6016005061, ISSN: 0003952018
C.PINA-VAZ, ET AL., J CLIN MICROBIOL, 2004, 42(2), PP906-908, JPN6016005057, ISSN: 0003952019
PINA-VAZ C: "CYTOMETRIC APPROACH FOR A RAPID EVALUATION OF SUSCEPTIBILITY OF CANDIDA STRAINS TO ANTIFUNGALS", CLINICAL MICROBIOLOGY AND INFECTION, vol. V7 N11, JPN5014007013, 1 November 2001 (2001-11-01), pages 609 - 618, ISSN: 0003952013
C.PINA-VAZ, ET AL., J MED MICROBIOL, 2001, 50, PP375-382, JPN6016005048, ISSN: 0003952014
A.FAVEL, ET AL., J ANTIMICROBIAL CHEMOTHERAPY, 1999, 43, PP227-232, JPN6016005050, ISSN: 0003952015
F.PEYRON, ET AL., ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41(7), PP1537-1540, JPN6016005052, ISSN: 0003952016
石井良和、モダンメディア、２００７年、５３巻４号、８−１４頁, JPN6016005055, ISSN: 0003952017
Attorney, Agent or Firm:
Creation International Patent Office
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