Title:
非経口アジュバントとしての細菌性ADP-リボシル化毒素の無毒化された変異体
Document Type and Number:
Japanese Patent JP3835826
Kind Code:
B2
Abstract:
The present invention provides parenteral adjuvants comprising detoxified mutants of bacterial ADP-ribosylating toxins, particularly those from pertussis (PT), cholera (CT), and heat-labile E. coli (LT).
Inventors:
Birchfeld, Gale
Dell Giudice, Giupsep
Lapuoli, Reno
Dell Giudice, Giupsep
Lapuoli, Reno
Application Number:
JP54327198A
Publication Date:
October 18, 2006
Filing Date:
March 19, 1998
Export Citation:
Assignee:
Chiron Corporation
International Classes:
A61K39/39; A61K9/06; A61K9/10; A61K9/107; A61K39/10; A61K39/106; A61K39/108; A61K39/145; A61K39/21; A61K39/245; A61P31/04; A61P31/12; A61P31/16; A61P31/18; A61P31/22; C07K14/235; C07K14/245; C07K14/28; A61K39/00
Domestic Patent References:
| JP2001508286A | ||||
| JP7506240A |
Foreign References:
| WO1995034323A1 | ||||
| WO1995017211A1 | ||||
| WO1997002348A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto