Title:
肥満症および関連障害の処置のための、選択的メラニン凝集ホルモンレセプターアンタゴニストとしての2置換ベンズイミダゾール誘導体。
Document Type and Number:
Japanese Patent JP4476291
Kind Code:
B2
Abstract:
The present invention discloses compounds of formula I wherein Ar, X, R1 and R11 are herein defined, said compounds being novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
Inventors:
Wu, Wen-Liang
Burnett, Duein A.
Caprene, mary anne
Burnett, Duein A.
Caprene, mary anne
Application Number:
JP2006524763A
Publication Date:
June 09, 2010
Filing Date:
August 23, 2004
Export Citation:
Assignee:
Schering Corporation
International Classes:
C07D401/06; A61K31/454; A61P3/00; A61P3/04; A61P3/06; A61P3/10; C07D401/14; C07D417/14
Domestic Patent References:
| JP11001481A | ||||
| JP2002541109A |
Foreign References:
| WO2003060475A1 | ||||
| WO2002076947A1 | ||||
| WO2002044141A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita