全フェノールに富む組成物を製造するための効果的方法

Japanese Patent JP2006511509

A

A product made by a process which results in compositions enriched in total phenols includes purification steps not involving the addition of bisulfite ions. The enriched compositions are characterized as containing monomeric, oligomeric and polymeric phenols, total phenol concentration >12% and exhibiting in vitro COX-2 inhibitory activity enhanced by a factor of at least 2.5 over a standard aspirin dose of 660 μg/mL.

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Goulden, Gerald, Tee.
Richheimer, Stephen, Elle.
Tempesta, Michael, S.
Bailey David, Tee.
Nichols, Rebecca
Doorty, F., Joseph
Freeburg, Delano, Earl.

JP2004555650A

April 06, 2006

November 21, 2003

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Phenolics, LRC

A61K31/353; A61K31/352; A61K31/70; A61K31/715; A61K36/18; A61K36/185; A61K36/28; A61K36/35; A61K36/45; A61K36/73; A61K36/736; A61K36/87; A61K45/00; A61P29/00; A61P31/00; A61P31/14; A61P31/16; A61P31/22; C07D311/62; A61K31/7048

JP2004507582A

2004-03-11

WO2002017945A1

2002-03-07

Hideto Asamura
Hajime Asamura
Katsunori Ando
Kameoka Mikio

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