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Title:
the -- the fused protein which has VII factor activity
Document Type and Number:
Japanese Patent JP6143297
Kind Code:
B2
Abstract:
A fusion protein comprising factor VII (FVII) and transferrin according to the present invention has an improved specific activity of FVII compared to existing FVII fusion proteins comprising other fusion partners than transferrin, and thus can be effectively used in a therapy using FVII.

Inventors:
Song, In Yoon
Kim, Hun Taek
Lee, Bon Young
Park, Man Hong
Lee, Ho Sung
Lim, Yoon Jun
Lee, The He
Song, Seo Yeon
Kim, Min Soon
Application Number:
JP2013513120A
Publication Date:
June 07, 2017
Filing Date:
June 07, 2011
Export Citation:
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Assignee:
TiumBio Co., Ltd.
International Classes:
C12N15/09; C07K14/745; C07K14/79; C07K19/00; C12N5/10
Domestic Patent References:
JP2005508623A
JP2009525724A
Foreign References:
US20060130158
WO2009158704A1
US20070072271
Other References:
J. Pharmacol. Exp. Ther. (2010) Vol.334, No.3, pp.682-692
Protein Expression and Purification (2008) Vol.61, No.1, pp.73-77
Attorney, Agent or Firm:
Kurata Masatoshi
Nobuhisa Nogawa
Naoki Kono
Tadashi Inoue
Ukai Ken
Shigeru Iino