Title:
HIV複製を抑制するためのグリシンアミド誘導体
Document Type and Number:
Japanese Patent JP2006518373
Kind Code:
A
Abstract:
The present invention relates to the discovery of a novel class of compounds that inhibit the replication of human immunodeficiency virus (HIV) and approaches to identify these compounds. More specifically, it has been found that enzymatically prepared alpha-hydroxyglycinamide and synthetically prepared alpha-hydroxyglycinamide inhibit the replication of HIV in human serum. Embodiments include methods to identify modified glycinamide compounds that inhibit HIV, methods to isolate and synthesize modified glycinamide compounds, and therapeutic compositions comprising these compounds.
Inventors:
Barzalini, Jean Maria Rene
Varne, Anders
Hogberg, Marita
Ton, waimin
Varne, Anders
Hogberg, Marita
Ton, waimin
Application Number:
JP2006502493A
Publication Date:
August 10, 2006
Filing Date:
February 19, 2004
Export Citation:
Assignee:
Tripep Acti Boraget
International Classes:
A61K31/16; A61K31/164; A61K31/27; A61K31/327; A61P31/18; C07C237/06; C07C409/40; B01D15/34; B01D15/36
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Mayuko Wakuda
Tsutomu Toyama
Hidemi Matsukura
Mayuko Wakuda
Tsutomu Toyama