Title:
ヒトインテグリン（アルファ－４）（ベータ－７）の阻害
Document Type and Number:
Japanese Patent JP2024054293
Kind Code:
A
Abstract:
【課題】α4β7インテグリンの阻害に有用な化合物を提供する。【解決手段】式(I)の化合物又はその塩を提供する。TIFF2024054293000582.tif58154式中、Ra、Rb及びRcは、H、Me、CF3、-(C1～C5)アルキレン-N-(Rx)(Ry)等；Rx及びRyは、H、(C1～C6)-アルキル等、又はそれらがNと共に4～6員環を形成；R1は、メチル、エチル等；R2は、置換フェニル基；R3a及びR3bは、H、(C1～C5)-アルキル等；R3c、R3d及びR4は、H。【選択図】なし
Inventors:
Bersavich, Matthew, Gee.
Cui, Dan
Dowling, James, Yee.
Hahn, Christopher, N.
Harrison, Bryce, A.
Lin, Fu-Yang
Ripper, Blaze, S.
Rogers, Bruce, N.
Trost, Dawn, M.
Zhong, Chen
Conz, Kyle, Dee.
Gelashute, Alexie, Ai.
Kim, Byungchan
Rafi, Salma
day, taylor
Hicky, Eugene
Howan, Evelyn
Zarah, Robert
Cui, Dan
Dowling, James, Yee.
Hahn, Christopher, N.
Harrison, Bryce, A.
Lin, Fu-Yang
Ripper, Blaze, S.
Rogers, Bruce, N.
Trost, Dawn, M.
Zhong, Chen
Conz, Kyle, Dee.
Gelashute, Alexie, Ai.
Kim, Byungchan
Rafi, Salma
day, taylor
Hicky, Eugene
Howan, Evelyn
Zarah, Robert
Application Number:
JP2024018765A
Publication Date:
April 16, 2024
Filing Date:
February 09, 2024
Export Citation:
Assignee:
Morphic Therapeutics, Incorporated
International Classes:
C07D401/06; A61K31/4412; A61K31/4427; A61K31/4439; A61P1/04; A61P43/00; C07D213/64
Attorney, Agent or Firm:
Patent Attorney Corporation Hiraki International Patent Office
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