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Title:
The improved gene therapy method
Document Type and Number:
Japanese Patent JP6066356
Kind Code:
B2
Abstract:
The present invention generally provides improved gene therapy vectors, cell-based compositions, and methods of using the same in methods of gene therapy. The present invention further provides improved gene therapy compositions for expanding hematopoietic cells and related methods for treatment of diseases, disorders, and conditions of the hematopoietic system such as thalassemias and anemias.

Inventors:
Ogre
Payyan, Emmanuel
Le Bourg, Philip
Buzzard, Eve
Application Number:
JP2014531777A
Publication Date:
January 25, 2017
Filing Date:
September 23, 2011
Export Citation:
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Assignee:
Bluebird Bio, Incorporated
International Classes:
C12N15/09; A61K35/28; A61K35/76; A61K48/00; A61P7/00; C12N5/10
Foreign References:
US20060057725
Other References:
NATURE, 2000, Vol. 406, pp. 82-86
BLOOD, 2000, Vol. 95, No. 12, pp. 3710-3715
PNAS, 1996, Vol. 93, pp. 9402-9407
Biochem. Biophys. Res. Commun., 1996, Vol. 218, pp. 205-209
ウイルス,2002,第52巻,第2号,pp.225-231
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto