Title:
An inhibitor of Thioredoxin interaction protein (TXNIP) for medical treatment
Document Type and Number:
Japanese Patent JP6078633
Kind Code:
B2
Abstract:
Described is a compound capable of reducing or inhibiting (a) the biological activity of thioredoxin-interacting protein (TXNIP) or (b) the expression of the gene encoding TXNIP for treating a condition where improving the resistance towards oxidative stress has a beneficial effect, e.g., for improving female fertiliy or extending healthy lifespan.
Inventors:
Clammer, peter
Gurou, Karsten
Thess, Sabine
Gurou, Karsten
Thess, Sabine
Application Number:
JP2015507410A
Publication Date:
February 08, 2017
Filing Date:
April 17, 2013
Export Citation:
Assignee:
DEUTSCHES KREBSFORSCHUNGSZENTRUM
International Classes:
C12N15/113; A61K31/7088; A61K39/395; A61K48/00; A61P15/08; C07K16/18; C12Q1/68; G01N33/15; G01N33/50
Foreign References:
| US20100272710 | ||||
| US20120058105 | ||||
| US20110097317 |
Other References:
Endocrinology,2004年,Vol.145, No.12,p.5485-5492
Attorney, Agent or Firm:
Patent business corporation r&c
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