Title:
体内に存在する病因物質の低下剤
Document Type and Number:
Japanese Patent JP5429804
Kind Code:
B2
Abstract:
To provide a drug for actively metabolizing or excreting a pathogen occurring in vivo. The present invention is directed to a compound which is formed of (A) an adsorbent for a pathogen occurring in the blood or lymph, and (B) a ligand which is specific to an organ or cells capable of metabolizing or excreting the pathogen and which is bonded to the adsorbent via a linker or with no linker, and to a drug containing the same.
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Inventors:
Tetsuji Yamaoka
Mariko Shiba
Atsushi Mahara
Yoshihito Kato
Mariko Shiba
Atsushi Mahara
Yoshihito Kato
Application Number:
JP2009534176A
Publication Date:
February 26, 2014
Filing Date:
September 25, 2008
Export Citation:
Assignee:
National Cardiovascular Research Center
Kowa Co., Ltd.
Kowa Co., Ltd.
International Classes:
A61K47/48; A61K31/737; A61K38/00; A61K39/395; A61K47/26; A61K47/44; A61P3/06; A61P7/08; A61P9/04; A61P9/10; A61P19/00; A61P19/02; A61P37/06; A61P39/02; A61P43/00
Domestic Patent References:
| JPH11509084A | 1999-08-17 | |||
| JPH11507046A | 1999-06-22 | |||
| JPH06269500A | 1994-09-27 | |||
| JPH01221400A | 1989-09-04 | |||
| JPH09266948A | 1997-10-14 | |||
| JP2002504831A | 2002-02-12 | |||
| JPH08253430A | 1996-10-01 |
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto