Title:
A manufacturing method of 1 and 3- Okisachio run nucleotide
Document Type and Number:
Japanese Patent JP5956492
Kind Code:
B2
Abstract:
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers.
Inventors:
Painter, George Earl.
Riotta, Dennis Sea.
Almond, Merrick
Clary, Daryl
Soria, Jose
Snydman, Marcos Lewis
Riotta, Dennis Sea.
Almond, Merrick
Clary, Daryl
Soria, Jose
Snydman, Marcos Lewis
Application Number:
JP2014061275A
Publication Date:
July 27, 2016
Filing Date:
March 25, 2014
Export Citation:
Assignee:
The Reed Sciences, Inc.
Emory University
Emory University
International Classes:
C07D411/04; A61K31/505; B01J31/02; C07D319/06; C07D327/04; C07D473/00
Domestic Patent References:
| JP5501117A |
Foreign References:
| WO1992010496A1 | ||||
| WO1992014729A1 |
Other References:
Journal of American Chemical Society,1991年,Vol.113, No.24,pp.9377-9379
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Jun Tsuruta
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima
Takashi Ishida
Jun Tsuruta
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima