Title:
1,3−オキサチオランヌクレオチドの製造方法
Document Type and Number:
Japanese Patent JP5547772
Kind Code:
B2
Abstract:
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers.
Inventors:
Painter, George R.
Rye オッタ, Dennis See.
An almond, Merrick
Clary, Darryl
Soria, Jose
スナイドマン, Marcos Lewis
Rye オッタ, Dennis See.
An almond, Merrick
Clary, Darryl
Soria, Jose
スナイドマン, Marcos Lewis
Application Number:
JP2012114415A
Publication Date:
July 16, 2014
Filing Date:
May 18, 2012
Export Citation:
Assignee:
ジリード Sciences, Incorporated
エモリー university
エモリー university
International Classes:
C07D317/34; A61K31/505; C07D319/06; C07D327/04; C07D411/04; C07D473/00; A61K31/513; A61P31/18
Attorney, Agent or Firm:
Aoki 篤
Ishida 敬
Tsuruta Junichi
Tsumoru Fukumoto
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Nakajima 勝
Ishida 敬
Tsuruta Junichi
Tsumoru Fukumoto
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Nakajima 勝