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Title:
1,3−オキサチオランヌクレオチドの製造方法
Document Type and Number:
Japanese Patent JP5547772
Kind Code:
B2
Abstract:
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers.

Inventors:
Painter, George R.
Rye オッタ, Dennis See.
An almond, Merrick
Clary, Darryl
Soria, Jose
スナイドマン, Marcos Lewis
Application Number:
JP2012114415A
Publication Date:
July 16, 2014
Filing Date:
May 18, 2012
Export Citation:
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Assignee:
ジリード Sciences, Incorporated
エモリー university
International Classes:
C07D317/34; A61K31/505; C07D319/06; C07D327/04; C07D411/04; C07D473/00; A61K31/513; A61P31/18
Attorney, Agent or Firm:
Aoki 篤
Ishida 敬
Tsuruta Junichi
Tsumoru Fukumoto
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Nakajima 勝



 
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