A manufacturing method of 1- [phenyl [2 - (2, 4- Dimethicone roux phenyl sulfanil) -]] - Piperazine

Title:

A manufacturing method of 1- [phenyl [2 - (2, 4- Dimethicone roux phenyl sulfanil) -]] - Piperazine

Document Type and Number:

Japanese Patent JP6018644

Kind Code:

B2

Abstract:

A process for the manufacture of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine and pharmaceutically acceptable salts is disclosed that involves reacting compounds of formula II, III, IV under Pd catalysis and in presence of phosphine ligands to give Compound I.

More Like This:

JP7472607	Liquid crystal composition and liquid crystal display element
WO/2007/078335	BIARYL NITROGEN HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION
WO/1994/000441	N(HETERO)-ARYL-N(HETERO)-TETRALIN-ALKYL-PIPERAZINE HAVING SEROTONINERGIC, DOPAMINERGIC AND ADRENERGIC ACTIVITY

Inventors:

Christensen, Kim, Lasse

Application Number:

JP2014550676A

Publication Date:

November 02, 2016

Filing Date:

December 20, 2012

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Her Lundbeck Actiezer Scabet

International Classes:

C07D295/096

Domestic Patent References:

JP2009541216A

Foreign References:

WO2010094285A1

Other References:

BENNY BANG-ANDERSEN,DISCOVEY OF 1-[2-(2, 4-DIMETHYLPHENYLSULFANYL)PHENYL]PIPERAZINE(LU AA21004): 以下省略,JOURNAL OF MEDICINAL CHEMISTRY,2011年 5月12日,V54 N9,P3206-3221
BENNY BANG-ANDERSEN,DISCOVEY OF 1-[2-(2, 4-DIMETHYLPHENYLSULFANYL)PHENYL]PIPERAZINE(LU AA21004): 以下省略,JOURNAL OF MEDICINAL CHEMISTRY [ONLINE],2011年 4月12日,V54 N9,P S1-S45,URL,http://pubs.acs.org/doi/suppl/10.1021/jm101459g/suppl_file/jm101459g_s1_001.pdf

Attorney, Agent or Firm:

Hiroshi Kobayashi
Norio Omori
Yasuhito Suzuki

Previous Patent: A manufacturing method of the bumper which has the bumper back beam and this in which the textiles c...

Next Patent: JPS6018645