Title:
A manufacturing method of a medical polyoxypropylene polymer, and a manufacturing method of medical polyoxypropylene / polyoxy ethylene block copolymer
Document Type and Number:
Japanese Patent JP6202471
Kind Code:
B2
Abstract:
To provide a medical polyoxypropylene polymer and a polyoxypropylene/polyoxyethylene block copolymer in which an unsaturated ether content is low and the coloring is suppressed. (A) To a polyoxypropylene polymer which is obtained by ring-opening polymerization of propylene oxide to a starting substance having an active hydrogen reacting with the propylene oxide and contains allyl ether as an impurity is added a tertiary alkoxide of alkali metal in an excess amount based on a molar number of the active hydrogen of the starting substance, followed by heat treating at 115°C or less to isomerize the allyl ether to propenyl ether; and (B) to the mixture obtained in the step (A) is added a mineral acid to adjust pH to 4 or less, followed by treating at 70°C or less to hydrolyze the propenyl ether.
Inventors:
Takuma Tatsuzaki
Yuji Yamamoto
Yuji Yamamoto
Application Number:
JP2013227328A
Publication Date:
September 27, 2017
Filing Date:
October 31, 2013
Export Citation:
Assignee:
NOF CORPORATION
International Classes:
C08G65/30; C08G65/26
Domestic Patent References:
| JP2007176847A | ||||
| JP2004315554A | ||||
| JP2007146191A | ||||
| JP11106500A |
Attorney, Agent or Firm:
Masumi Hosoda
Juno Aoki
Juno Aoki